5% to 7% of jojoba press-cake are Simmondsins, Dimethylsimmondsin has been found to suppress appetite. Angiogenesis inhibiting properties are under study by oncology researchers induced by other simmondsin derivates present in jojoba meal as desmethyl and didesmethyl-simmondsin and the simmondsin ferulates.

Simmondsins will be produced on demand.